Anti-Glutamate Supplements: Protect Yourself Against The Damage

Glutamate is the most important neurotransmitter for the brain’s normal function. Do you know that you need it to form memories?

Assorted supplements

You probably knew that monosodium glutamate or MSG scare most people but the fact is you need to have enough glutamate. Your body has abundant of this amino acid called glutamate, high concentrations are right there in your brains and muscles. It plays an important function in firing up brain cells and as building blocks for proteins. You just need enough glutamate, not more, and not less. As glutamate accelerates brain activity, its partner GABA does the opposite because it is an inhibitory brain chemical. In a balanced state, together they keep the brain operates at its right place. Overactivated nerve cells can die, too much glutamate causes cell destruction. To protect your brain nerve cells, you will need anti-glutamate supplements.

Benefits of Glutamate

Aids the function of the brain

As the most significant neurotransmitter for your brain’s normal function, it is the main excitatory neurotransmitter as well. It functions by sending signals to other brain and body cells aiding in memory, cognitive, and brain development. The glutamate in the brain is produced inside the brain cells and not from dietary glutamate.  

Glutamate is a precursor for GABA

GABA or gamma-aminobutyric acid is an inhibitory neurotransmitter, functions as the opposite to glutamate. To produce GABA, the body utilizes glutamate with the help of the enzyme Glutamic Acid Decarboxylase. The body needs GABA as it is a calming neurotransmitter balancing glutamate’s function.   

Improves the digestive system, appetite, and satiation

Glutamate that you get from the food stimulates GUT triggering movement as it is the main source of energy of the cells in this part of the body. Ingesting food with glutamate signals the body that it is getting protein-rich food, increasing appetite, and the MSG makes the bland food tasty.   

Plays part in Immunity

Glutamate receptors such as T cells, B cells, dendritic and macrophages are existing in the immune cells. It increases autoimmune T cells that are anti-inflammatory.   

Linked with bone health 

Amino acid glutamate is essential for bone growth and development. Aids in the treatment of some bone diseases like osteoporosis.

Vital for muscle function.

Glutamate detoxifies muscle cells. This non-essential amino acid help treat fatigue and muscular dystrophy.   

Excess in Glutamate

In excess, glutamate becomes a powerful excitotoxin by overworking the brain cells causing possible brain damage. There are two causes of glutamate excess:

  1. Accumulation of too much glutamate
  2. Receptors are oversensitive causing these neurotransmitters easily get to be overstimulated    

Negative effects of excess glutamate

  • Neurological Disorders.
  • Epilepsy
  • Depression
  • Multiple sclerosis and amyotrophic lateral sclerosis
  • Neurodegenerative Diseases
  • Traumatic Brain Injuries
  • Cancer Pain
  • Diabetes
  • Migraine

Anti-Glutamate Supplements

Below are anti-glutamate supplements you can get to protect yourself before the damage.


A good anti-glutamate supplement you can get from meat, fish, dairy, and as an artificial supplement. It is called a conditional amino acid which means can naturally produce in the body, which has multiple brain-protective properties. It serves as protection to brain cells from excitotoxicity and enhances the relaxing neurotransmitter GABA opposing excitotoxic impact. In the case wherein there is a traumatic brain injury, taurine protects the brain cells from damage after a stroke. 


A powerful medicinal herb and an anti-glutamate supplement that enhance brain function and improves neurodegenerative diseases like Alzheimer’s disease and Parkinson’s disease. Ginger roots are a rich source of antioxidants and anti-inflammatory properties that is good for the neurodegenerative condition.    

Vitamin C

Vitamin C prevents neurons glutamate overstimulation that’s is why it’s a good anti-glutamate supplement. Certain plants and animals can produce vitamin C, humans and other mammals need to get it from nutrition.

Coenzyme Q10

A rich source of antioxidants is another anti-glutamate supplement because it protects the cells from the damage of oxidative stress. You can get coenzyme Q10 or Ubiquinol/ubiquinone eating fish or buy the supplement if you don’t get it from the food you eat.   


Pyrroloquinoline Quinone or PQQ helps guard the brain against threats of damage and stimulates new cell growth through nerve growth factor (NGF). This is another anti-glutamate supplement. NGF is a small protein molecule that is needed for the maintenance and growth of a nerve cell vital for memory and learning.

Valerian Root

This is a good anti-glutamate supplement because it is a sedative herb, increases GABA, therefore, it reduces glutamate actions. If GABA is increased it offset the actions of glutamate.


L-theanine is a compound from black tea and green tea, available in supplement form. This anti-glutamate supplement because increases GABA and relieves anxiety as well as insomnia.   

Vitamin B6

Part of the B complex vitamins that helps the central nervous system (CNS), one of its functions is to improve brain performance. As an anti-glutamate supplement, vitamin B6 is needed for the brain’s neuron transmission. Many foods contain B6 and a well-balanced diet should keep you away from B6 deficiency.       

The anti-glutamate supplement can protect you from damage. Too much glutamate or too little is dangerous and the balance between neurotransmitters of glutamate and GABBA is needed for beneficial function. 

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